Cirius Therapeutics

Developing a next-generation insulin sensitizer for the treatment of NASH

Cirius Therapeutics (formerly Octeta Therapeutics) is developing MSDC-0602K, a next-generation insulin sensitizer, for the treatment of nonalcoholic steatohepatitis (NASH). NASH affects approximately 16 million Americans, and untreated can progress to cirrhosis and liver transplant. MSDC-0602K is currently being evaluated in a Phase 2b clinical trial. Through its novel insulin sensitizing mechanism of action, MSDC-0602K has potential to resolve the underlying pathophysiology of NASH. The company is led by Frazier EIRs Bob Baltera, Howard Dittrich, and Brian Farmer.

Year of Investment
Life Sciences
San Diego, California